OFF!® Botanicals® Insect Repellent IV is a bug spray that contains the synthetically engineered active ingredient found in eucalyptus plants but derived from pine oil. Protect your skin from mosquitoes before one even buzzes in your direction. OFF!® Botanicals® Insect Repellent Spritz repels mosquitoes, black flies, gnats, and no-see-ums. Repel mosquitoes that may carry West Nile virus with this spritz. To apply, spray directly onto skin or, for sensitive areas, it can be sprayed onto hands and then applied to the skin.